Pathological Fractures in Neoplastic Disease: Causes, Symptoms, and Treatment

Pathological fracture in neoplastic disease is a condition characterized by the occurrence of bone fractures caused by underlying cancerous tumors. Neoplastic diseases refer to the abnormal growth of tumors that can be either benign or malignant. In this case, the tumors invade the bones, weakening their structure and making them prone to fractures even with minimal trauma or stress.

Pathological fractures are different from regular fractures as they occur in weakened bones due to the presence of tumors. These fractures can happen in any bone affected by the neoplastic disease, but common sites include the long bones of the arms and legs, the spine, and the hips.

Symptoms of pathological fractures may include sudden, severe pain at the fracture site, swelling, deformity, and limited mobility. Diagnosis is typically made through imaging tests such as X-rays, CT scans, or MRI scans.

Treatment options for pathological fractures in neoplastic disease depend on various factors, such as the type and stage of the cancer, the location and severity of the fracture, and the overall health of the patient. Treatment may involve surgery to stabilize the fracture, radiation therapy to target the tumor, chemotherapy to control cancer spread, and supportive measures to improve bone healing and overall well-being.